Event ID - 4001

Event Id4001
SourceDNS
DescriptionThe DNS server was unable to open zone <zone mane> in the Active Directory. This DNS server is configured to obtain and use information from the directory for this zone and is unable to load the zone without it. Check that the Active Directory is functioning properly and reload the zone. The event data is the error code.
Event InformationCheck DNS Server configurations are correct. Then check AD is running properly.
In most of the cases it may able fix this problem by Netdiag /fix command. if you are not able to fix this problem by this command try to recreate the Sysvol folder structure.
Reference LinksDNS Server Does Not Start with DBCS Domain Names

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