Event ID - 300

Event Id300
SourceCOMTI
Description300) COM Transaction Integrators state machine dispenser was unable to create a new state machine object

Progress Code: 6
HRESULT: 0x80040111
Event InformationCOMTI components that use an LU 6.2-type Remote Environment may fail under load and log events 103, 300, and 301 in the application event log.
CAUSE:
Under load, multiple COMTI client requests may be received at or near the same time. If this occurs when COMTI tries to load the APPC transport DLLs (wappc32.dll and wincsv32.dll), a timing issue may occur, which causes COMTI to return an exception to the client and to log the events that are listed in the "Symptoms" section.

Following MS article will give more information about this event.
Reference LinksCOMTI May Log Events 103, 300, and 301 When Under Load

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