Event ID - 4151

Event Id4151
SourceMSExchnageIMC
DescriptionAn inbound mail message was not accepted on <Exch.MyDomain.com>because the authentication account did not have permission to use the originator address on the message.
Event InformationAccording to Microsoft :
CAUSE
The problem occurs because the Netscape client adds the RFC-822 header "SENDER", populated by the users logon name from the foreign system. This does not match the authentication account, which was in the format: Ntdomain\Ntaccount, and Exchange Server rejects the submission. This occurs if either or both of the above client restrictions are enabled.
WORKAROUND:
To resolve this problem, edit the Preferences.js file located in the hidden directory ".netscape", in the users home directory on the IRIX workstation. This is a Netscape preferences file that instructs the Netscape client whether to send the SENDER header information. Editing this file can suppress sending this header information. To edit this file, perform the following steps:
1. Open the Preferences.js file using a plain text editor, and verify that the following entry exists:
Pref("mail.suppress_sender_header", true);
2. If the entry is set to "false", edit the entry so that it appears as in step 1 above.
If you are not able to edit this file, there is an alternate workaround. (NOTE: This workaround retains the client restrictions for all hosts except those specified in the workaround):
1. In Microsoft Exchange Administrator, view the Internet Mail Service properties.
2. Click the Connections tab, Click Accept connections, and then click Hosts.
3. Click Add, and type the IP address and subnet mask of the IRIX host using Netscape. If you want authentication, specify it here. 4. Select the "This host is a relay server" check box.
5. Stop and start the Internet Mail Service.
This workaround must be performed for each IRIX host that will be submitting SMTP mail to the Exchange Server computer with the Netscape Communicator client.
Note that setting the IRIX host as a relay server will override the security settings in the Connections property sheet.
Reference LinksIRIX Netscape POP3/IMAP4 Client Cannot Submit SMTP Mail

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